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Isolation of an oxalate-resistant Ashbya gossypii strain and its improved riboflavin production
http://hdl.handle.net/10297/5172
http://hdl.handle.net/10297/51720ba807a0-3147-4afd-8288-72e377d1c99c
名前 / ファイル | ライセンス | アクション |
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100702002.pdf (392.8 kB)
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Item type | 学術雑誌論文 / Journal Article_01(1) | |||||||||
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公開日 | 2010-07-02 | |||||||||
タイトル | ||||||||||
言語 | en | |||||||||
タイトル | Isolation of an oxalate-resistant Ashbya gossypii strain and its improved riboflavin production | |||||||||
言語 | ||||||||||
言語 | eng | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Bioreactors | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Biotechnology | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Culture Media | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Drug Resistance, Fungal | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Fungal Proteins | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Industrial Microbiology | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Isocitrate Lyase | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Kinetics | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Oxalic Acid | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Proteome | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Riboflavin | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Saccharomycetales | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Spores, Fungal | |||||||||
資源タイプ | ||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
資源タイプ | journal article | |||||||||
著者 |
Sugimoto, Takashi
× Sugimoto, Takashi× Morimoto, Aki× Nariyama, Masashi× Kato, Tatsuya
WEKO
2910
× Park, Enoch Y.
WEKO
2907
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書誌情報 |
Journal of industrial microbiology & biotechnology 巻 37, 号 1, p. 57-64, 発行日 2010-01 |
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出版者 | ||||||||||
出版者 | Springer | |||||||||
権利情報 | ||||||||||
権利情報 | The original publication is available at www.springerlink.com | |||||||||
NDC | ||||||||||
主題Scheme | NDC | |||||||||
主題 | 474 | |||||||||
抄録 | ||||||||||
内容記述タイプ | Abstract | |||||||||
内容記述 | An oxalate-resistant strain of Ashbya gossypii was naturally isolated from spores grown on an oxalate-containing medium, and its medium was optimized to improve riboflavin production. Riboflavin production by the resistant strain was three-fold higher than that by the wild-type organism when grown in flask cultures. Medium optimization increased the riboflavin production by the resistant strain to 5 g l(-1), which was five-fold higher than that obtained by the wild-type strain. The productivity was reproduced in a 3-l bioreactor. During the early growth phase, the specific activity of isocitrate lyase in the oxalate-resistant strain was slightly higher than that in the wild-type strain. Proteomic analysis of the oxalate-resistant strain revealed that the expression of aldose reductase and cobalamin-independent methionine synthase decreased significantly. This is the first report that describes the natural isolation of a riboflavin producer using an antimetabolite-containing medium to enhance the riboflavin production level. This method should also be useful for improving the productivity of other bioproducts since it does not require any mutations or genetic modifications of the microorganism. | |||||||||
ISSN | ||||||||||
収録物識別子タイプ | ISSN | |||||||||
収録物識別子 | 13675435 | |||||||||
EISSN | ||||||||||
収録物識別子タイプ | ISSN | |||||||||
収録物識別子 | 14765535 | |||||||||
NII書誌ID | ||||||||||
収録物識別子タイプ | NCID | |||||||||
収録物識別子 | AA11132053 | |||||||||
PubMed番号 | ||||||||||
関連タイプ | isIdenticalTo | |||||||||
識別子タイプ | PMID | |||||||||
関連識別子 | 19826846 | |||||||||
出版者DOI | ||||||||||
関連タイプ | isIdenticalTo | |||||||||
識別子タイプ | DOI | |||||||||
関連識別子 | 10.1007/s10295-009-0647-3 | |||||||||
フォーマット | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | application/pdf | |||||||||
著者版フラグ | ||||||||||
出版タイプ | VoR | |||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |