{"created":"2023-07-25T10:33:28.184831+00:00","id":4847,"links":{},"metadata":{"_buckets":{"deposit":"caf0f08f-c6f2-4cb1-83e0-918408db64af"},"_deposit":{"created_by":3,"id":"4847","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"4847"},"status":"published"},"_oai":{"id":"oai:shizuoka.repo.nii.ac.jp:00004847","sets":["23:221"]},"author_link":["4920","2179","2179"],"control_number":"4847","item_26_biblio_info_5":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"52","bibliographicPageStart":"41","bibliographicVolumeNumber":"87","bibliographic_titles":[{"bibliographic_title":"Proceedings of the Japan Academy. Series B","bibliographic_titleLang":"en"}]}]},"item_26_description_30":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_26_description_9":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Erabutoxins a and b are neurotoxins isolated from venom of a sea snake Laticauda semifasciata (erabu-umihebi). Amino acid sequences of the toxins indicated that the toxins are members of a superfamily consisting of short and long neurotoxins and cytotoxins found in sea snakes and terrestrial snakes. The short neurotoxins to which erabutoxins belong act by blocking the nicotinic acetylcholine receptor on the post synaptic membrane in a manner similar to that of curare. X-ray crystallography and NMR analyses showed that the toxins have a three-finger structure, in which three fingers made of three loops emerging from a dense core make a gently concave surface of the protein. The sequence comparison and the location of essential residues on the protein suggested the mechanism of binding of the toxin to the acetylcholine receptor. Classification of snakes by means of sequence comparison and that based on different morphological features were inconsistent, which led the authors to propose a hypothesis \"Evolution without divergence.\"(Communicated by Satoshi OMURA, M.J.A.).","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_26_publisher_6":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"The Japan Academy","subitem_publisher_language":"en"}]},"item_26_relation_22":{"attribute_name":"NII論文ID","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"130000669109","subitem_relation_type_select":"NAID"}}]},"item_26_relation_26":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"21422738","subitem_relation_type_select":"PMID"}}]},"item_26_relation_28":{"attribute_name":"出版者DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.2183/pjab.87.41","subitem_relation_type_select":"DOI"}}]},"item_26_rights_7":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2011 The Japan Academy"}]},"item_26_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03862208","subitem_source_identifier_type":"ISSN"}]},"item_26_source_id_20":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"13492896","subitem_source_identifier_type":"ISSN"}]},"item_26_source_id_23":{"attribute_name":"NII書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA00785485","subitem_source_identifier_type":"NCID"}]},"item_26_subject_8":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"464","subitem_subject_scheme":"NDC"}]},"item_26_version_type_32":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Tamiya, Nobuo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4920","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yagi, Tatsuhiko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2179","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"00021882","nameIdentifierScheme":"KAKEN - 研究者検索","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/nrid/1000000021882/"},{"nameIdentifier":"2179","nameIdentifierScheme":"wekoID","nameIdentifierURI":"https://shizuoka.repo.nii.ac.jp/?action=pages_view_main&active_action=repository_view_main_item_snippet&meta=&wekoAuthorId=2179&count=20&order=16&pn=1&page_id=13&block_id=21"},{"nameIdentifier":"b75733b8-304e-4211-af7f-2efa44c30846","nameIdentifierScheme":"著者リンク","nameIdentifierURI":"http://uni.lib.shizuoka.ac.jp/Record/b75733b8-304e-4211-af7f-2efa44c30846"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-12-14"}],"displaytype":"detail","filename":"110413001.pdf","filesize":[{"value":"564.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"110413001.pdf","url":"https://shizuoka.repo.nii.ac.jp/record/4847/files/110413001.pdf"},"version_id":"d9214986-f197-41ac-a34c-23269e10fd67"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Studies on sea snake venom","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Studies on sea snake venom","subitem_title_language":"en"}]},"item_type_id":"26","owner":"3","path":["221"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2011-04-13"},"publish_date":"2011-04-13","publish_status":"0","recid":"4847","relation_version_is_last":true,"title":["Studies on sea snake venom"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2025-01-22T06:16:56.938874+00:00"}