@article{oai:shizuoka.repo.nii.ac.jp:00004855,
 author = {Todoroki, Yasushi and Narita, Kenta and Muramatsu, Taku and Shimomura, Hajime and Ohnishi, Toshiyuki and Mizutani, Masaharu and Ueno, Kotomi and Hirai, Nobuhiro},
 issue = {5},
 journal = {Bioorganic & Medicinal Chemistry},
 month = {Mar},
 note = {application/pdf, We prepared 19 amino acid conjugates of the plant hormone abscisic acid (ABA) and investigated their biological activity, enzymatic hydrolysis by a recombinant Arabidopsis amidohydrolases GST-ILR1 and GST-IAR3, and metabolic fate in rice seedlings. Different sets of ABA-amino acids induced ABA-like responses in different plants. Some ABA-amino acids, including some that were active in bioassays, were hydrolyzed by recombinant Arabidopsis GST-IAR3, although GST-ILR1 did not show hydrolysis activity for any of the ABA-amino acids. ABA-L-Ala, which was active in all the bioassays, an Arabidopsis seed germination, spinach seed germination, and rice seedling elongation assays, except in a lettuce seed germination assay and was hydrolyzed by GST-IAR3, was hydrolyzed to free ABA in rice seedlings. These findings suggest that some plant amidohydrolases hydrolyze some ABA-amino acid conjugates. Because our study indicates the possibility that different plants have hydrolyzing activity toward different ABA-amino acids, an ABA-amino acid may function as a species-selective pro-hormone of ABA.},
 pages = {1743--1750},
 title = {Synthesis and biological activity of amino acid conjugates of abscisic acid.},
 volume = {19},
 year = {2011}
}