{"created":"2023-07-25T10:33:29.630480+00:00","id":4877,"links":{},"metadata":{"_buckets":{"deposit":"738e2fb6-5edd-461b-9cf2-0df0fff7f602"},"_deposit":{"created_by":3,"id":"4877","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"4877"},"status":"published"},"_oai":{"id":"oai:shizuoka.repo.nii.ac.jp:00004877","sets":["80:222"]},"author_link":["5021","5022","5020","5023"],"item_26_biblio_info_5":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-04-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"14","bibliographicPageStart":"145102","bibliographicVolumeNumber":"134","bibliographic_titles":[{"bibliographic_title":"Journal of Chemical Physics"}]}]},"item_26_description_30":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_26_description_9":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Recently, it has been well recognized that the modulation of electrostatic interactions due to surface charges can induce transitions between lamellar liquid-crystalline (L(α)) and inverse bicontinuous double-diamond cubic (Q(II) (D)) phases in biological lipids. To reveal their kinetic pathway and mechanism, we investigated the low pH-induced L(α) to Q(II) (D) phase transitions in 20%-dioleoylphosphatidylserine (DOPS)/80%-monoolein (MO) using time-resolved small-angle x-ray scattering and a rapid mixing method. At a final pH of 2.6-2.9, the L(α) phase was transformed completely into the hexagonal II (H(II)) phase within 2-10 s after mixing a low pH buffer with a suspension of multilamellar vesicles of 20%-DOPS∕80%-MO (the initial step). Subsequently, the H(II) phase slowly converted into the Q(II) (D) phase and completely disappeared within 15-30 min (the second step). The rate constants of the second step were obtained using the singular value decomposition analysis. On the basis of these data, we discuss the underlying mechanism of the kinetic pathway of the low pH-induced L(α) to Q(II) (D) phase transitions.","subitem_description_type":"Abstract"}]},"item_26_publisher_6":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"American Institute of Physics"}]},"item_26_relation_26":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"21495771","subitem_relation_type_select":"PMID"}}]},"item_26_relation_28":{"attribute_name":"出版者DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1063/1.3575240","subitem_relation_type_select":"DOI"}}]},"item_26_rights_7":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2011 American Institute of Physics"}]},"item_26_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00219606","subitem_source_identifier_type":"ISSN"}]},"item_26_source_id_23":{"attribute_name":"NII書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA00694991","subitem_source_identifier_type":"NCID"}]},"item_26_subject_8":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"464","subitem_subject_scheme":"NDC"}]},"item_26_version_type_32":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Alam, Mahay Md."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Oka, Toshihiko"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"Ohta, Noboru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamazaki, Masahito"}],"nameIdentifiers":[{},{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-12-14"}],"displaytype":"detail","filename":"110519001.pdf","filesize":[{"value":"782.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"110519001.pdf","url":"https://shizuoka.repo.nii.ac.jp/record/4877/files/110519001.pdf"},"version_id":"a4805464-962c-4e55-8600-de9b07d8206a"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Kinetics of low pH-induced lamellar to bicontinuous cubic phase transition in dioleoylphosphatidylserine/monoolein","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Kinetics of low pH-induced lamellar to bicontinuous cubic phase transition in dioleoylphosphatidylserine/monoolein","subitem_title_language":"en"}]},"item_type_id":"26","owner":"3","path":["222"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-05-19"},"publish_date":"2011-05-19","publish_status":"0","recid":"4877","relation_version_is_last":true,"title":["Kinetics of low pH-induced lamellar to bicontinuous cubic phase transition in dioleoylphosphatidylserine/monoolein"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2024-02-14T02:48:26.329340+00:00"}